Natural product drug discovery from microalgae

Together with Mark Brönstrup from sanofi-aventis I have written a chapter on “Natural product drug discovery from microalgae” for the book “Microalgal Biotechnology: Integration and Economy“, edited by C. Posten and C. Walter, published by de Gruyter.

I know that this is behind the pay wall – I have signed the author contract before I became Aware of Open… If you want to have a copy of the chapter, just drop me a line. I would be happy about comments on the chapter from anyone interested in this topic.

Edit: What I have learned – Insist on imprimatur. Complicated story why, but the legend of figure 10.8 is wrong and should only read “Mechanism of toxin release from antibody-drug conjugates.”. I have written an email to the publisher and hope that this can be corrected at least in the pdf version of the chapter. After all, it is their mistake that the legend is flawed…

Edit 2: They will correct the figure caption for the pdf file. Thank you, de Gruyter.

How “open” are natural product scientists? Part I – Conference Talks

Four months ago I visited a fantastic conference, the International Conference on Natural Product Research 2012, ICNPR 2012, in New York. It was one of the best conferences I ever visited. I presented two posters there which I later uploaded to figshare (can be downloaded here and here).

Many of the talks were really interesting, and after the conference I contacted 12 speakers if they would share their presentation so that I could have another look at the slides and recapitulate what I had learned.

2 of the scientists answered that they are not willing to share their slides, because some of the material has not been published, yet. Hugh?! How can someone make a publication out of some PowerPoint slides?! And who would be stupid enough to try? And what about those guys in the audience that took pictures of every single slide of every single talk?

Well, at least these two were more polite than the 5 scientists who did not answer at all, even when after a few weeks I kindly remembered them that I had interest to have a second look at their presentations…

This leaves 5 scientists who sent their talks, 3 of them after friendly reminders. Good luck for me that these were the most interesting talks! Funnily enough, 4 of these 5 are professors at the Scripps Institution of Oceanography in San Diego. It might be that American scientists are more willing to share than others; but not all professors from the States I asked did share, though…

Of course this has not been a systematic study of the willingness to share among natural product scientists, but it made me wonder why it is not common standard that all talks are made available to conference attendants after conferences. This would make the experiences of visiting a conference even more pleasant and would enhance the learning effects dramatically.

After making this experience, I decided to share all talks I give, whether people want it or not. 🙂 And I chose figshare as a platform for this. Of course a slide set is less informative than listening to the talks themselves (especially because sometimes I prefer to show only large pictures and spend some time talking around them…), but anyways…

To put my money where my mouth is: Some weeks ago I talked about „Cyanobacteria in Anticancer Natural Product Research” at the annual meeting of the German Pharmaceutical Society 2012 in Greifswald, Germany. Anyone interested can now have a look at the slides at figshare. If you have any questions on the slides or on cyanobacteria in general, don’t hesitate to comment this blog post or directly the slides at figshare.